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KMID : 0360319860180010014
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Journal of Korean Cancer Research Association
1986 Volume.18 No. 1 p.14 ~ p.20
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A Clinical Study on 45 Cases of Small and Non-Small Cell Lung Cancer
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김우중/Kim, Woo Joong
송춘의/전영수/문한림/홍영선/김훈교/김호연/Song, Choon Ik/Jun, Young Soo/Moon, Hanlim/Hong, Young Seon/Kim, Hoon Kyo/Kim, Ho Yun
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Abstract
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A clinical study of 45 patients admitted with a diagnosis of small and non-small cell lung cancer to the Kang Nam St. Mary´s Hospital from NOV. 1982 to Dec. 1984 revealed the following results.
1) Among the 45 patients, 11 patients were classified as small cell cancer and 34 patients as non-small cell cancer with the highest incidence in the 6th to 8th decade.
2) The male/female ratio in small cell cancer and non-small cell cancer was 10 : 1 and 2.1 : 1 respectively showing male predominance in small cell cancer. The smoker/mon-smoker ratio in small and non-small cell cancer was 4 : 1 and 2.1 : 1 respectively showing smoker predominance in small cell cancer.
3) Coughing was the most common symptom in both small and non small cell cancer, but symptom due to regional spread was not statistically different between two groups.
4) In the location of tumor, 72.7% of small cell cancer and 58.1% of non-small cell cancer were located in the central area showing more central distribution in small cell cancer.
5) Metastasis to the bone and brain was more frequent in small cell cancer, but metastasis to the lymph node and bone marrow was more frequent in non-small cell cancer, although which was not statistically significant.
6) 8 cases(72%) of small cell cancer and 17 cases(50%) of non-small cell cancer were diagnosed by bronchoscopy showing higher rate of detection by broochoscopy in small cell cancer.
And 2 cases(18.2%) of small cell cancer and 14 cases(29.4%) of non-small cell cancer were diagnosed by lymph node biopsy showing higher rate of detection by lymph node biopsy in non-small cell cancer.
7) Among the 5 cases of limited type-small cell cancer, partial and complete remission occurred in 3 cases(60%), 2 cases(40%) respectively showing mean survival of more than 14.3 months. And among the 4 cases of extensive type-small cell cancer, 2 cases(50%) who showed partial remission lived 6 months and 2 cases(50%) who showed no response lived 3.5 months.
8) 29 cases(85.3%) of non-small cell cancer were stage 3 at the time of diagnosis in which 13 cases(81%) of squmous cell cancer, 9 cases (82%) of adenocarcinoma and 7 cases(100%) of undifferentiated cell cancer were being included.
9) In the review of survival duration of non-small cell cancer, 10 cases(76.9%) of response group showed mean survival of more than 7 months and 3 cases(23. 1%) of non-response group lived 2.2 months.
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KEYWORD
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